Friday, April 15, 2016

HIV overcomes CRISPR gene-editing attack


We all got really excited a few weeks ago when researchers announced they’d removed HIV from human immune cells using new gene-editing technology called CRISPR/Cas-9, or ‘CRISPR’ for short, which works like a pair of molecular scissors to cut and paste DNA.

As far as we know, that specific result is holding up just fine, but a separate study has now revealed that, worryingly, HIV can evolve to survive CRISPR attacks in just two weeks. Even worse, the attack itself could actually be introducing mutations that make the virus stronger.


Paper:http://www.nature.com/news/hiv-overcomes-crispr-gene-editing-attack-1.19712?WT.mc_id=TWT_NatureNews

Article:http://www.sciencealert.com/hiv-took-just-2-weeks-to-overcome-our-best-attempts-to-edit-it-out-of-our-cells


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